Every year millions of people travel from the industrialized countries to the developing countries. Traveller’s Diarrhoea (TD) is a common syndrome affecting healthy travellers not only in developing countries but also in Europe. The incidence of TD ranges from 20 to 50% depending on the origin and the destination of the traveller as well as the mode of travel (1,2). TD is defined as the passage of ≥3 unformed stools in a 24 h period and although it is often self-limiting, there is a considerable morbidity (3,4). Approximately 3% of international travellers to high-risk areas develop persistent diarrhoea. By definition the duration of persistent diarrhoea is at least 14 days, but it may last several months to a year. In approximately 50% of travellers with persistent diarrhoea, it lasts more than 30 days (5). However, even when the diarrhoea is self-limiting, minor attacks can interrupt a holiday, causing inconvenience and discomfort (1).