Influence of the Multispecies Probiotic Ecologic® BARRIER on Parameters of Intestinal Barrier Function

Year: 2014

Journal: Food and Nutrition Sciences

Authors: Saskia van Hemert Geline Ormel


The intestinal epithelium is a single cell layer that forms the largest and most important barrier against the external environment. A proper functioning of the intestinal barrier is essential for maintaining optimal health. A disrupted intestinal barrier function has been associated with the development of autoimmune and inflammatory diseases. Probiotics are live microorganisms that confer a health benefit to the host and have been associated with prevention of diseases such as antibiotic-associated diarrhea, irritable bowel syndrome and inflammatory bowel disease. Probiotics can improve and restore the intestinal barrier function in diverse ways and effects are thought to be species- and even strain-specific. With this research the influence of probiotic bacteria in Ecologic® BARRIER on parameters of intestinal barrier function was investigated. The results show that each bacterial strain in Ecologic® BARRIER is in vitro capable to improve the epithelial barrier in diverse ways.

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Food and Nutrition Sciences