Are you looking for a probiotic that exactly fits your demands? We are always ready to listen to your wishes and develop a tailor-made formulation in collaboration with you. Depending on your requirements, customized solutions can be developed for a broad or a specific indication. As for our large collection of bacterial strains and species, we can potentially develop every thinkable probiotic formulation.
For each formulation, we extensively screen the probiotic strains and select only those strains that possess relevant probiotic characteristics. It is also possible to incorporate other, active ingredients such as vitamins, in the formulations. Our probiotic formulations are developed from a scientific background, which includes literature research and (in vitro) research.
All our probiotics are manufactured in a GMP-certified facility and tested for excellent efficacy. After production, we can guarantee a 1-2 year stability at room temperature. To insure and ensure this high quality, both our products and the manufacturing processes are controlled by certified, external laboratories.
All of our probiotic strains are naturally derived, typically of human origin, and have the QPS (Qualified Presumption of Safety) status or an extensive safety file.
Our probiotic solutions are available both as bulk deliveries and as finished products, ready to market under your own brand.
Two famous strains in Winclove’s extensive collection of bacteria strains are Lactobacillus Plantarum W1 (virtually identical to Lactobacillus plantarum WCFS1 ) and Propionibacterium freudenreichii W200. These bacterial strains possess unique properties which make them excellent candidates to incorporate in probiotic formulations that stand out in the market.
Lactobacillus plantarum W1
Lactobacillus plantarum W1 is one of the best studied Lactobacilli. The complete genome of this bacteria has been mapped. L. plantarum W1 can be cultured to high densities, is amenable to genetic transformations and enjoys a robustness that ensures a relatively high survival rate during the gastro-intestinal passage.
The versatile character of L. plantarum W(CFS)1, together with its fully known genome and the tremendous amount of research data, makes it a model organism and extremely suitable for a range of indications. The strain seems to have potential to:
- Treating elevated cholesterol levels
- Restoring increased intestinal permeability
- Stimulating TH1 cells and/or regulatory T cells
Propionibacterium freudenreichii W200
Propionibacterium freudenreichii W200 contains sufficient amounts of natural vitamin B12 to make an EFSA approved vitamin B12 claim. P. freudenreichii W200 produces and stores vitamin B12 in its cells during the fermentation process.. Winclove has upgraded the fermentation
process of P. freudenreichii W200 in such a way that the bacterium contains large amounts of natural vitamin B12 This makes it possible to make an EFSA health claim on your probiotic formulations without adding other functional ingredients.