New innovation: probiotic strain produces natural vitamin B12 for EFSA health claim
We have succeeded in upgrading the fermentation process of Propionibacterium freudenreichii W200 in such a way that the bacterium now contains adequate amounts of vitamin B12 to make an EFSA validated vitamin B12 health claim.
According to the WHO probiotics are defined as “live micro-organisms which, when administered in adequate amounts, confer a health beneﬁt on the host". Although this definition is widely adopted, European national regulatory authorities forbid the use of the word “probiotic” since it embeds a non-validated health claim. So far, EFSA has rejected all submitted health claims for probiotics. However, the upgraded Propionibacterium freudenreichii W200 contains adequate amounts of vitamin B12 to make a validated vitamin B12 health claim. This would be the first strain with an approved health claim, implying the first probiotic that can truly be called a probiotic.
With the upgraded Propionibacterium freudenreichii W200 the following 8 EFSA health claims can be made:
· Vitamin B12 contributes to the reduction of tiredness and fatigue
· Vitamin B12 contributes to the normal function of the immune system
· Vitamin B12 contributes to normal functioning of the nervous system
· Vitamin B12 contributes to normal psychological function
· Vitamin B12 contributes to normal energy-yielding metabolism
· Vitamin B12 contributes to normal red blood cell formation
· Vitamin B12 contributes to normal homocysteine metabolism
· Vitamin B12 has a role in the process of cell division
We have optimized the fermentation process of Propionibacterium freudenreichii W200 in such a way that it now produces substantial amounts of vitamin B12. Vitamin B12, also called cobalamin, is involved in the metabolism of every cell of the human body and is only produced through a bacterial fermentation-synthesis. Propionibacteria are already known for producing vitamin B12, however in small amounts.
The advice on daily intake of vitamin B12 differs per age-group and daily Dietary Reference Intakes differ per country. In Europe, EFSA decided that a health claim may be used if a daily dose of 0,375mcg vitamin B12 is added to the product. Our upgraded Propionibacterium freudenreichii W200 can provide this daily dose of vitamin B12. The bacterium is on the QPS (qualified presumption of safety status) list.
We are very pleased with the first successful steps in this innovation. If you are interested in this innovation we would be more than happy to discuss the opportunities for your market.
For more information please contact Rianne Hagen; firstname.lastname@example.org.