The mouth is one of the most heavily colonised parts of our bodies, harbouring an estimated 600+ different bacterial species. A balanced oral microbiota protects the mouth from infections and contributes to the maintenance of oral health. However, the oral microbiota can be easily disturbed by factors such as; poor oral hygiene, lifestyle choices including dietary habits and smoking, immunodeficiency, and time. These disturbances can cause dental carries (dental decay) and periodontal diseases, such as gingivitis (inflammation of the gingivae) and in more severe cases periodontitis (gum disease).8 Furthermore, an association has been found between the composition of the oral microbiota and systemic disease, such as cardiovascular disease and pregnancy complications.
Harmfull bacteria assemble in a biofilm and cause inflammation of the periodental tissue
Oral diseases start with the growth of dental plaque, a biofilm formed by the accumulation of bacteria and their toxins together with saliva. Current treatment of plaque and oral diseases involve mouthwashes and professional teeth cleaning, and in more advanced cases antibiotics or surgery. However, with ever increasing antibiotic resistance and their unwanted side effects such as antibiotic-associated diarrhoea, there is an increased need for novel therapies that do not involve conventional antimicrobial agents.
Probiotics have therapeutic potential in the management of carries and periodontal diseases, since they prevent dysbiosis by inhibiting growth of periodontal pathogens and modulating disease associated inflammatory pathways. Several meta-analyses have found significant effectiveness for the use of probiotics in the management of oral health and gingivitis.
Winclove offers the following probiotic formulations aimed at improving oral health
|Improvement of oral health and prevention of gingivitis|